Serotonin syndrome: Instances of serotonin syndrome, a potentially life-threatening condition, happen to be reported during concomitant utilization of opioids with serotonergic drugs.
People that take Dilaudid, In particular at high doses, have a high danger of overdose because of the potency from the medication. The drug slows down breathing and respiratory function, to The purpose that it can be potentially lethal and cause respiratory arrest. Symptoms of overdose include:
Hydromorphone also calls for careful administration in people using selective serotonin reuptake inhibitors or tricyclic antidepressants a result of the potential hazard of serotonin syndrome.
Keep an eye on individuals for indications of respiratory depression That could be bigger than otherwise expected and decrease the dosage of DILAUDID INJECTION and/or perhaps the muscle relaxant as required.
Like Dilaudid, oxycodone should only be used when other alternatives are usually not suitable or can not be tolerated.
It from time to time seems in assays of opium latex in incredibly smaller quantities, evidently forming in the plant within an unknown proportion of instances under badly understood problems.[citation required]
Opioid use increases the potential risk of CSA inside a dose-dependent vogue. In patients who present with CSA, consider reducing the opioid dosage applying ideal practices for opioid taper [see DOSAGE AND ADMINISTRATION].
Inspect parenteral drug merchandise visually for particulate subject and discoloration previous to administration, whenever solution and container permit. A slight yellowish discoloration could acquire in DILAUDID INJECTION.
Observe newborns for indications of neonatal opioid withdrawal syndrome and manage accordingly. Advise Expecting women applying opioids for an extended period of time of the potential risk of neonatal opioid withdrawal syndrome and be sure that management by neonatology authorities will be readily available at delivery [see Use In Certain Populations].
Respiratory depression can take place at any time during opioid therapy, In particular when initiating and subsequent dosage increases with DILAUDID INJECTION. Consider this danger when selecting an First dose and when making dose adjustments [see WARNINGS AND PRECAUTIONS].
Drinking alcohol, having prescription or nonprescription medications that have alcohol, or having illegal drugs during oxycodone treatment method can increase the potential risk of extreme troubles.
Each of these drugs also can produce overdose and are very risky for children. Continue to keep your medication locked and absent from any kids in your domestic. Because hydromorphone is so potent, it may be fatal if a youngster takes just one ER tablet.
Dilaudid takes effect within quarter-hour, and its pain-relieving effects lasts up to six hrs. Dilaudid is pattern forming and is dilaudid et alcool commonly abused amongst individuals for its potent euphoric effects, which has been referred to as being similar to that of Heroin.
Using an opioid medicine for many time during pregnancy can cause a withdrawal syndrome in the infant when the baby is born. This may be life-threatening if not dealt with.